EVE Online - Player-created empires, player-driven markets, and endless ways to embark on your personal sci-fi adventure.
Endless Space - Endless Space is an Amazing, Strategy, Science-fiction, Turn-based, Space, Futuristic, Exploration, Co-op, Single and Multiplayer Space Simulation created and published by Amplitude Studios.
Star Trek Online - Star Trek Online (STO) is a free to play MMORPG that takes place inside the Star Trek world.
Sins Of A Solar Empire - Sins of a Solar Empire is an Adventure, Strategy, Real-time-strategy, Science-fiction, Exploration, Aliens, Single and Multiplayer Space Simulation developed by Ironclad Games and published by Stardock.
Ace Online - Ace Online is a distinctive 3D MMO that places you in the pilot seat of your personal fighter ship (called a Gear).
Stellaris - Stellaris is an Adventure-based, RTS (Real-time Strategy) Space, Sandbox, Sci-Fi, Single and Multiplayer video game created and published by Paradox Interactive.