Unity - The multiplatform game creation tools for everyone.
Spirit - The animation tool for the web.
Godot Engine - Feature-packed 2D and 3D open source game engine.
Lottie by Airbnb - Easily add high-quality animation to any native app
Blender - Blender is the open source, cross platform suite of tools for 3D creation.
Haiku Animator - Create powerful animations for any app or website