Unity - The multiplatform game creation tools for everyone.
pixeldudesmaker - Simple, web-based pixel art character generator.
Godot Engine - Feature-packed 2D and 3D open source game engine.
RPG Character Builder - Create thousands of unique character sprites for your 2D game project - free!
Blender - Blender is the open source, cross platform suite of tools for 3D creation.
Game Character Hub - helper program for game design (RPG Maker XP/VX and more)