While I realize this does nothing for mobile (RIP third-party clients), Control Panel for Twitter [1] has been nice for me to use as a browserscript. Defaults/hides "For You" and tweaks a bunch of other stuff (hideable trends, etc). [1]: https://github.com/insin/control-panel-for-twitter. - Source: Hacker News / 10 months ago

Idk for mobile, but for desktop - one such example. Source: 11 months ago

Open Twitter from desktop browser only and use an extension to tailor your experience. Source: 11 months ago

Install the Control Panel extension to banish that shit. No "for you" feed. For the love of God, no trending topics. Read stuff from the people you follow and nowhere else. Source: 12 months ago

On desktop, there are extensions that can help, like Control Panel for Twitter. Source: about 1 year ago

Semiphemeral used to be able to do this, but only if you had previously downloaded your entire twitter data archive. Source: about 1 year ago

Https://semiphemeral.com/ is what I have been using for this for a while, but always good to have more options. - Source: Hacker News / over 1 year ago

You can also use Semiphemeral to delete all your tweets too for good measure. Source: over 1 year ago

The rogues at https://semiphemeral.com may be able to aid you in your quest. Source: almost 2 years ago

Semiphemeral is a project by /u/micahflee who is the Director if Information Security at The Intercept and also the developer of OnionShare and Dangerzone. Source: about 2 years ago