Mastercam - Mastercam's Dynamic Milling is a game changer for us.
LTspice - LTspice® is a high performance SPICE simulation software, schematic capture and waveform viewer with enhancements and models for easing the simulation of analog circuits.
Autodesk Fusion 360 - Integrated CAD, CAM, and CAE featuring collaborative editing and cloud-based computation.
TINACloud - Create Simulate and Design Circuits and their PCB layout with TINACloud
Vectric Aspire - The complete software solution for CNC Routing,
EasyEDA - EasyEDA - Web-based EDA suite; runs in browser.