FHEM - FHEM (TM) is a GPL'd perl server for house automation.
AWS IoT - Easily and securely connect devices to the cloud.
Conrad Connect - Service for managing smart home devices
Particle.io - Particle is an IoT platform enabling businesses to build, connect and manage their connected solutions.
pimatic - Home automation framework that runs on node.js.
AWS Greengrass - Local compute, messaging, data caching, and synch capabilities for connected devices