Homeworld - Homeworld is an Action-Adventure, Science-fiction, Real-time Strategy, Real-time-tactical, Single and Multiplayer Space Simulation created by Relic Entertainment and published by Sierra Entertainment.
Empyrion - Empyrion is a 3D open world, space survival adventure in which you can fly across space and land on...
Stellaris - Stellaris is an Adventure-based, RTS (Real-time Strategy) Space, Sandbox, Sci-Fi, Single and Multiplayer video game created and published by Paradox Interactive.
StarMade - StarMade is a Minecraft inspired 3D space shooter.
Endless Space - Endless Space is an Amazing, Strategy, Science-fiction, Turn-based, Space, Futuristic, Exploration, Co-op, Single and Multiplayer Space Simulation created and published by Amplitude Studios.
EVE Online - Player-created empires, player-driven markets, and endless ways to embark on your personal sci-fi adventure.