Scilab is recommended for engineers, scientists, and educators who require a powerful computational tool without the associated costs of commercial software. It is also suitable for students and researchers who are looking to perform complex mathematical modeling and simulations.
MATLAB - A high-level language and interactive environment for numerical computation, visualization, and programming
AnyLogic - AnyLogic has changed simulation modeling and expanded its application into complex business environments. The unmatched flexibility of multimethod modeling allows users to capture the complexity of virtually any system, at any level of detail.
Wolfram Mathematica - Mathematica has characterized the cutting edge in specialized processing—and gave the chief calculation environment to a large number of pioneers, instructors, understudies, and others around the globe.
FlexSim - Simulation software to model, simulate, predict, and visualize systems in manufacturing, material handling, healthcare, warehousing, mining, etc.
GNU Octave - GNU Octave is a programming language for scientific computing.
Simio - Facility design simulation & production scheduling