EtherCalc - EtherCalc is a web spreadsheet.
Microsoft Office Excel - Microsoft Office Excel is a commercial spreadsheet application.
FlexiSheet - FlexiSheet is a multi-dimensional spreadsheet in the spirit of Lotus Improv.
Google Sheets - Synchronizing, online-based word processor, part of Google Drive.
Pyspread - pyspread is a non-traditional spreadsheet application that is based on and written in the programming language Python.
Apple Numbers - Numbers lets you build beautiful spreadsheets on a Mac, iPad, or iPhone — or on a PC using iWork for iCloud. And it’s compatible with Apple Pencil.