Qiqqa is by far the strongest solution for research and managing pdf's. Zotero, named as a comparison is weak as it does not allow pdf;s to be loaded into its interface - you need to use a pdf reader, which defeats its whole purpose. With Qiqqa documents in a library can be searched together. It has excellent maps of your libraries. It is not prefect, having a few glitches, but still is the only one of its kind.
Mendeley - Easily organize your papers, read & annotate your PDFs, collaborate in private or open groups, and securely access your research from everywhere.
MAXQDA - a professional software for qualitative and mixed methods data analysis
Zotero - Zotero is a free, easy-to-use tool to help you collect, organize, cite, and share research.
NVivo - Buy NVivo now for flexible solutions to meet your specific research and data analysis needs.
JabRef - Graphical Java application for managing bibtex (. bib) databases.JabRef · JabRef Help · JabRef | Blog · OpenOffice/LibreOffice .
QualCoder - A very complete Free and Open Source Software (FOSS) Computer-Assisted Qualitative Data Analysis Software (CAQDAS) written in Python. It works with text, images, and multimedia such as audios and videos.