Aseprite - Aseprite is an art program dedicated to the creation of pixel art.
VistaCreate - The VistaCreate is a free and global digital platform which is known for sharing, searching, finding, and creating great art.
Pixelorama - Free and open source sprite editor and animator, ideal for pixel art.
IconLover - Icon editor for Windows.
Piskel - Piskel is a website where designers online create sprites or pixel art.
Art Set 4 - Art Set 4 is the extravagant and intelligent Painting and drawing application that facilitates you to create drawings or painting with the help of a variety of different features and functionalities.