iDempiere - iDempiere Business Suite ERP/CRM/SCM done the community way.
Clio - Clio provides a full suite of web-based practice management tools targeted specifically at the administrative needs of sole practitioners and small firms.
DataNote ERP - DataNote ERP is a complete ERP solution built for multiple industries such as construction, engineering, food and beverages, metal processing, and healthcare, among others.
MyCase - Practice More, Manage Less.
PracticePanther - PracticePanther offers CRM, invoicing, time tracking and communication solutions for law firms.
Xpenditure - Xpenditure is a mobile and web-based expense management system.