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Inkscape - Inkscape is a free, open source professional vector graphics editor for Windows, Mac OS X and Linux.
Sketch - Professional digital design for Mac.
LaTeXDraw - LaTeXDraw is a graphical drawing editor for LaTeX.
Ipe - Ipe is a drawing editor for creating figures in PDF or (encapsulated) Postscript format.
Adobe Photoshop - Adobe Photoshop is a webtop application for editing images and photos online.
Graphviz - Graphviz is open source graph visualization software. It has several main graph layout programs.