Jira may be extremely sluggish and require a large amount of memory on the client side.
Steward Database - Steward is a personal database for organizing everything. It's easy to use.
Trello - Infinitely flexible. Incredibly easy to use. Great mobile apps. It's free. Trello keeps track of everything, from the big picture to the minute details.
Philasmicos Contacts 2 - Philasmicos Contacts is a professional business relationships management system for macOS X.
Asana - Asana project management is an effort to re-imagine how we work together, through modern productivity software. Fast and versatile, Asana helps individuals and groups get more done.
iDatabase for Mac - The intuitive personal database manager.
Wrike - Wrike is a flexible, scalable, and easy-to-use collaborative work management software that helps high-performance teams organize and accomplish their work. Try it now.