Sins Of A Solar Empire - Sins of a Solar Empire is an Adventure, Strategy, Real-time-strategy, Science-fiction, Exploration, Aliens, Single and Multiplayer Space Simulation developed by Ironclad Games and published by Stardock.
X3: Terran Conflict - X3: Terran Conflict is part of the X number of video games.
Space Station 13 - Space Station 13 is a Ton-Down, Role-playing, Space and Multiplayer video game set on a futuristic space station where the player can choose to play from a selection of different jobs.
Star Trek Online - Star Trek Online (STO) is a free to play MMORPG that takes place inside the Star Trek world.
Endless Space - Endless Space is an Amazing, Strategy, Science-fiction, Turn-based, Space, Futuristic, Exploration, Co-op, Single and Multiplayer Space Simulation created and published by Amplitude Studios.
DarkStar One - DarkStar One is targeted on space trading and combat.