JabbR - A chat application built with ASP.NET and SignalR.
The Lounge - The Lounge is a web IRC client that you host on your own server.
AvatarPalace - AvatarPalace is the platform that is used for a chat with others in a 2D virtual world and provides various cartoon characters and fun avatars for a chat.
Konversation - Konversation is an IRC client which gives you speedy access to Freenode network's channels...
MyENIGMA - MyENIGMA is an app that allows you to send text messages, videos, audio clips, photos, and files to your friends and family securely.
irssi - Irssi is a terminal based IRC client for UNIX systems.