DeepSkyStacker might be a bit more popular than Neat Image. We know about 1 link to it since March 2021 and only 1 link to Neat Image. We are tracking product recommendations and mentions on various public social media platforms and blogs. They can help you identify which product is more popular and what people think of it.
Neat Image does a good job with this image. You create a noise profile by manually sampling areas of the image with uniform noise and use that to build a noise profile. Here's the image with noise reduction applied: Google drive. Source: almost 2 years ago
So, according to deep sky stacker darks and bias frames remove different kinds of noise. It says nothing of them working against each other. Source: over 2 years ago
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