Vectric Aspire - The complete software solution for CNC Routing,
Blender - Blender is the open source, cross platform suite of tools for 3D creation.
Autodesk Fusion 360 - Integrated CAD, CAM, and CAE featuring collaborative editing and cloud-based computation.
FreeCAD - An open-source parametric 3D modeler
Autodesk ArtCAM - ArtCAM is a cad/cam software program thats been designed for artisans instead of engineers.
LibreCAD - An open source 2D CAD application for Windows, Apple and Linux.