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Atomic FE - Atomic FE is a Front-End for Multi-emulators.
1Password - 1Password can create strong, unique passwords for you, remember them, and restore them, all directly in your web browser.
HyperSpin - HyperSpin is an animated arcade frontend for Windows for use on Home Arcade Machines.
Lastpass - LastPass is an online password manager and form filler that makes web browsing easier and more secure.
GameEx - GameEx is considered to be the most powerful and feature rich front-end for MAME, GameBase, Daphne, PC Games and all command line based game emulators, along with being a complete Home Theatre PC solution.
KeePass - KeePass is an open source password manager. Passwords can be stored in highly-encrypted databases, which can be unlocked with one master password or key file.