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Thunderbird - Thunderbird is a free email application that's easy to set up and customize - and it's loaded with great features!
Postbox - The Power Email App for busy professionals, like you.
Microsoft Outlook - Organize your world. Outlook’s email and calendar tools help you communicate, stay on top of what matters, and get things done.
Mailpile - Mailpile is a modern, fast web-mail client with user-friendly encryption and privacy features.
eM Client - eM Client is a fully-featured email client for Windows and macOS with a clean and easy-to-use interface. eM Client also offers features for calendars, tasks, contacts, notes, and chat.
Zimbra Desktop - Zimbra Desktop is an offline client that lets you manage various email accounts in one desktop tool. Zimbra mail, Yahoo! mail, Gmail, Outlook and any other work or personal email account using POP or IMAP is easy to set up in Zimbra Desktop.