LinuxCNC (the Enhanced Machine Control) - LinuxCNC: an open source CNC machine controller. It can drive milling machines, lathes, 3d printers, laser cutters, plasma cutters, robot arms, hexapods, and more.
MoI - Moment of Inspiration - MoI is a new 3D Modeling/CAD application for designers and artists. Offering a blend of precision and freeform NURBS drawing tools, it sports a unique user interface that operates seamlessly with a pen tablet.
Vectric Aspire - The complete software solution for CNC Routing,
Jewelry CAD Dream - JCD is a powerful and robust jewelry design solution.
Mastercam - Mastercam's Dynamic Milling is a game changer for us.
Rhinojewel - Rhinojewel is a Jewelry Design Software which lets you create 3D models of jewelry and other luxury items easily, precisely and quickly. Jewelry Modeling Tools for Designers.