LinuxCNC (the Enhanced Machine Control) - LinuxCNC: an open source CNC machine controller. It can drive milling machines, lathes, 3d printers, laser cutters, plasma cutters, robot arms, hexapods, and more.
Sketch - Professional digital design for Mac.
Vectric Aspire - The complete software solution for CNC Routing,
Inkscape - Inkscape is a free, open source professional vector graphics editor for Windows, Mac OS X and Linux.
Mastercam - Mastercam's Dynamic Milling is a game changer for us.
Adobe Photoshop - Adobe Photoshop is a webtop application for editing images and photos online.