VTube Studio - VTube Studio is an app for Virtual YouTubers that makes VTubing easy and fun!!
Blender - Blender is the open source, cross platform suite of tools for 3D creation.
VSeeFace - VSeeFace is a free, highly configurable face and hand tracking VRM and VSFAvatar avatar puppeteering program for virtual youtubers with a focus on robust tracking and high image quality
Autodesk 3DS Max - 3ds Max is software for 3D modeling, animation, rendering, and visualization. Create stunning game enrivonments, design visualizations, and virtual reality experiences.
MakeHuman - MakeHuman is a free, open source, interactive modeling tool for creating custom 3D human characters.
Cinema 4D - Cinema 4D is a 3D modeling, animation, motion graphics and rendering application.