Blender - Blender is the open source, cross platform suite of tools for 3D creation.
pixeldudesmaker - Simple, web-based pixel art character generator.
Cinema 4D - Cinema 4D is a 3D modeling, animation, motion graphics and rendering application.
RPG Character Builder - Create thousands of unique character sprites for your 2D game project - free!
V-Ray - Learn why V-Ray for 3ds Max’s powerful CPU & GPU renderer is the industry standard for artists & designers in architecture, games, VFX, VR, and more.
Universal LPC Spritesheet Character Generator - Powerful, animated character generator for creating 2D spritesheets