Jira may be extremely sluggish and require a large amount of memory on the client side.
Trello - Infinitely flexible. Incredibly easy to use. Great mobile apps. It's free. Trello keeps track of everything, from the big picture to the minute details.
DisplayFusion - DisplayFusion will make your multi-monitor life much easier.
Asana - Asana project management is an effort to re-imagine how we work together, through modern productivity software. Fast and versatile, Asana helps individuals and groups get more done.
WindowGrid - Quickly and easily layout windows on a dynamic grid using just the mouse.
Wrike - Wrike is a flexible, scalable, and easy-to-use collaborative work management software that helps high-performance teams organize and accomplish their work. Try it now.
Mizage Divvy - Divvy is an entirely new way of managing your workspace.