ioBroker - flexible and modular application for the IoT and Smarthome
openHAB - "empowering the smart home" - vendor and technology agnostic open source home automation
Domoticz - Domoticz is a lightweight Home Automation System
Home-Assistant.io - Home Assistant is an open-source home automation platform running on Python 3.
mediola IQONTROL - A Home Gadget, IoT Hub for multiple devices and vendors
Homebridge.io - Homebridge is a lightweight NodeJS server you can run on your network that emulates the iOS HomeKit...