WinCDEmu - WinCDEmu is an open-source CD/DVD/BD emulator.
DAEMON Tools - The most personal application for disc imaging yet.
Virtual CloneDrive - Virtual CloneDrive works and behaves just like a physical CD/DVD/Blu-ray drive, although it only exists virtually.
MagicISO - MagicISO is a powerful CD/DVD image file creating/editing/extracting tool.
UltraISO - CD image files are easily created with UltraISO.
PowerISO - PowerISO is a virtual drive that allows users to encode, burn, mount, and even encrypt CDs, DVDs, and BDs. The software can be downloaded from many platforms and sites online.