Grasshopper 3D - Grasshopper™ is a graphical algorithm editor tightly integrated with Rhino’s 3-D modeling tools.
Unity - The multiplatform game creation tools for everyone.
DYNAMO BIM - An open-source platform for computational design and for building information modeling (BIM).
Godot Engine - Feature-packed 2D and 3D open source game engine.
Houdini - Houdini covers all the major areas of 3D production, including:
Blender - Blender is the open source, cross platform suite of tools for 3D creation.