Healthcare.gov - Since the healthcare law took full effect this year, HealthCare.
Loomio - Loomio helps groups of people make decisions together, online.
TravelInsurance.com - Travel insurance application.
DemocracyOS - DemocracyOS is an open source application for online decision making.
Split Pic - Clone yourself and create collages!
Airesis - A decision making tool for direct democracy and e-government: participate in discussions, bring your ideas, suggest solutions and vote online