Campaign Cartographer - Campaign Cartographer is the leading map making software for games (RPGs, miniatures and wargaming).

Sprite Fusion - Design your game with Sprite Fusion, the ultimate free online tilemap editor. Design 2D games with ease, direclty export to Unity Tilemap and Godot Scenes. Ideal for retro games!

PyMapper - Drag and drop tile based mapping program.

Aseprite - Aseprite is an art program dedicated to the creation of pixel art.

Dungeon Tile Mapper - Dungeon Tile Mapper is a web based tile mapping tool that includes many official D&D tile sets.

LibreSprite - Free and open source program to create animated sprites.