Invision - Prototyping and collaboration for design teams
Unity - The multiplatform game creation tools for everyone.
Balsamiq - Balsamiq. Rapid, effective and fun wireframing software.
Godot Engine - Feature-packed 2D and 3D open source game engine.
Moqups - The most stunning HTML5 app for creating resolution-independent SVG mockups, wireframes & interactive prototypes for your next project
Blender - Blender is the open source, cross platform suite of tools for 3D creation.