Open Rails - Open Rails is an open source simulator that is designed to run Microsoft Train Simulator content.
Trainz Simulator - Trainz Simulator is a commercial train simulator from Australia.
openBVE - openBVE is an open source train simulator
BVE trainsim - BVE trainsim is a train simulator based on the point of view of the train operator.
Train Sim World - Master iconic locomotives on high-speed services, long freight hauls or precise commuter traffic, and get creative with customisation tools in this advanced sequel. Climb into the cab in Train Sim World 2.
Dovetail Games Train Simulator - Dovetail Games Train Simulator is a commercial train simulator.