Mach3 - Mach3 is very popular among the Hobby CNC community.
Blender - Blender is the open source, cross platform suite of tools for 3D creation.
LinuxCNC (the Enhanced Machine Control) - LinuxCNC: an open source CNC machine controller. It can drive milling machines, lathes, 3d printers, laser cutters, plasma cutters, robot arms, hexapods, and more.
Autodesk 3DS Max - 3ds Max is software for 3D modeling, animation, rendering, and visualization. Create stunning game enrivonments, design visualizations, and virtual reality experiences.
SolidCAM - The ‘Best-in-Class’ CAM Solution for Efficient & Profitable CNC-Programming Inside Your CAD
ZBrush - ZBrush is a digital sculpting and painting software solution.