PyMapper - Drag and drop tile based mapping program.
Inkarnate - A free-form map editor for role-playing games, focusing on overland and continental maps.
Fractal Mapper - With Fractal Mapper, creating worlds has never been so easy!
Wonderdraft - is an intuitive yet powerful fantasy map creation tool for 64-bit Windows 10, Linux, and MacOSX.
Tiamat - Tiamat is Web 2.0 Tile Mapper; Ideal for creating miniature scale maps for role playing and miniature games.
Campaign Cartographer - Campaign Cartographer is the leading map making software for games (RPGs, miniatures and wargaming).