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Spine - Spine is 2D animation software designed specifically for software and game development.
Tiled Map Editor - Tiled is a general purpose tile map editor.
Live2D Cubism - Live2D is the world's first drawing technology to enable 3D rendering of 2D images.
Tilesetter - The tileset designing software.
Synfig Studio - Just another WordPress site
AnimeEffects - AnimeEffects is a 2D keyframe animation tool based on deformation of polygon meshes.