PyQt - Riverbank | Software | PyQt | What is PyQt?
PySimpleGUI - A simple to use GUI that can create custom GUIs
Tkinter - Tkinter is a Python wrapper for Tcl/Tk that offers classes to create various graphical user interfaces.
GTK - GTK+ is a multi-platform toolkit for creating graphical user interfaces.
BeeWare - Write your apps in Python and release them on iOS, Android, Windows, MacOS, Linux, Web, and tvOS...
PyGObject - PyGObject is a python extension module that allows Python programs to easily interface and make use of libraries using the GObject type system.