Spine - Spine is 2D animation software designed specifically for software and game development.
Synfig Studio - Just another WordPress site
FaceRig - FaceRig is a program that aims to enable anyone with a webcam to digitally embody awesome...
Unity 2D - Unity 2D is a powerful and feature-rich game design solution built from the ground up to fulfill every basic and advanced need of the developer.
MocapX - Facial Motion capture app Maya and iPhone. With the MocapX animator, you can easily use the iPhone camera to animate characters in real time directly in Maya. MocapX tools enable you to use any custom or production rig as well as any Maya feature.
Blender - Blender is the open source, cross platform suite of tools for 3D creation.