Godot Engine - Feature-packed 2D and 3D open source game engine.
Electron - Build cross platform desktop apps with web technologies
Unreal Engine - Unreal Engine 4 is a suite of integrated tools for game developers to design and build games, simulations, and visualizations.
NW.js - nwjs
BYOND - BYOND is the premier community for making and playing online multiplayer games.
NeutralinoJS - Neutralino is a lightweight application development framework.