The Lounge - The Lounge is a web IRC client that you host on your own server.
JabbR - A chat application built with ASP.NET and SignalR.
Konversation - Konversation is an IRC client which gives you speedy access to Freenode network's channels...
Chattp - Chattp is the software that simply converts your page into chat by augmenting the browser Windows.
irssi - Irssi is a terminal based IRC client for UNIX systems.
MyENIGMA - MyENIGMA is an app that allows you to send text messages, videos, audio clips, photos, and files to your friends and family securely.