Blender - Blender is the open source, cross platform suite of tools for 3D creation.
LDraw - LDraw is an open standard for LEGO CAD programs that allow the user to create virtual LEGO models...
Autodesk 3DS Max - 3ds Max is software for 3D modeling, animation, rendering, and visualization. Create stunning game enrivonments, design visualizations, and virtual reality experiences.
LeoCAD - LeoCAD is a CAD program for creating virtual LEGO models.
ZBrush - ZBrush is a digital sculpting and painting software solution.
Stud.io - Build LEGO designs online with friends.