Gwibber - Gwibber is an open source microblogging client for GNOME developed with Python and GTK.
TweetDeck - TweetDeck is your personal browser for staying in touch with what’s happening now.
Tweetbot - Sync your timeline across your iPhone, iPad, and Mac. Mute tweets by user, hashtag, tweet source, or keywords (including regex). 3rd Party support for image, video, read later, and timeline sync services.
Earthquake - Terminal-based Twitter Client with Streaming API support. Only supports Ruby 1.9 and later.
YoruFukurou - YoruFukurou (NightOwl) is a Twitter client for Mac OS X, designed for Twitter addicts.
Oysttyer - Oysttyer is a console text-based command-line Twitter client and Perl platform, fork of...