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Gwibber - Gwibber is an open source microblogging client for GNOME developed with Python and GTK.
Typefully - Write & publish great tweets, without distractions
TweetDeck - TweetDeck is your personal browser for staying in touch with what’s happening now.
Tweet Tray - Tweet quickly from your desktop without any distractions.
Tweetbot - Sync your timeline across your iPhone, iPad, and Mac. Mute tweets by user, hashtag, tweet source, or keywords (including regex). 3rd Party support for image, video, read later, and timeline sync services.
Minimal Twitter - A distraction-free browsing experience for the new Twitter