Gwibber - Gwibber is an open source microblogging client for GNOME developed with Python and GTK.
Socialite - History Ever since we acquired Socialite from Realmac Software in December 2010, we have been planning on releasing a faster, more stable version 2.
TweetDeck - TweetDeck is your personal browser for staying in touch with what’s happening now.
mybucketz - “mybucketz” is your social media unified.
Tweetbot - Sync your timeline across your iPhone, iPad, and Mac. Mute tweets by user, hashtag, tweet source, or keywords (including regex). 3rd Party support for image, video, read later, and timeline sync services.
Postling - A tool that makes it easy to manage all of your social media from a single interface