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MATLAB - A high-level language and interactive environment for numerical computation, visualization, and programming
Blender - Blender is the open source, cross platform suite of tools for 3D creation.
Onshape - Onshape is the first full-cloud 3D CAD system. It runs in a web browser and on any mobile device.
FreeCAD - An open-source parametric 3D modeler
Wolfram Mathematica - Mathematica has characterized the cutting edge in specialized processing—and gave the chief calculation environment to a large number of pioneers, instructors, understudies, and others around the globe.
LibreCAD - An open source 2D CAD application for Windows, Apple and Linux.