Blender - Blender is the open source, cross platform suite of tools for 3D creation.
I Know It - "I Know It" is an online game for practicing primary-level math concepts.
Cinema 4D - Cinema 4D is a 3D modeling, animation, motion graphics and rendering application.
GCompris - Educational Game for Children 2 to 10 years old.
Autodesk Maya - Maya is 3D computer animation software with powerful modeling, rendering, simulation, texturing, and animation tools for artists, modelers, and animators.
childsplay - Childsplay is a collection of educational activities for young children and runs on Windows, OSX, and Linux. Childsplay can be used at home, kindergartens and pre-schools.