Blender - Blender is the open source, cross platform suite of tools for 3D creation.
LeoCAD - LeoCAD is a CAD program for creating virtual LEGO models.
Cinema 4D - Cinema 4D is a 3D modeling, animation, motion graphics and rendering application.
LDraw - LDraw is an open standard for LEGO CAD programs that allow the user to create virtual LEGO models...
Autodesk Maya - Maya is 3D computer animation software with powerful modeling, rendering, simulation, texturing, and animation tools for artists, modelers, and animators.
LDCad - LDCad is a multiplatform ...