Blender - Blender is the open source, cross platform suite of tools for 3D creation.
Gimel Studio - Next-generation of the cross-platform non-destructive, node based 2D image graphics editor
Cinema 4D - Cinema 4D is a 3D modeling, animation, motion graphics and rendering application.
GIMP - GIMP is a multiplatform photo manipulation tool.
Autodesk Maya - Maya is 3D computer animation software with powerful modeling, rendering, simulation, texturing, and animation tools for artists, modelers, and animators.
PixaFlux - PixaFlux is a node based image processing application.