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Spine - Spine is 2D animation software designed specifically for software and game development.
Synfig Studio - Just another WordPress site
Creature - Creature 2D Skeletal and Mesh Animation Tool
Unity 2D - Unity 2D is a powerful and feature-rich game design solution built from the ground up to fulfill every basic and advanced need of the developer.
Animation Paper - Animation Paper is a software package for doing 2D animation.
DigiCel FlipBook - Whether you do 2D, 3D or stop motion Animation, DigiCel FlipBook makes animation easier!