eMule - eMule is a free peer-to-peer file sharing application for Microsoft Windows.
DC++ - DC++ developed by Jacek Sieka.
Soulseek - Soulseek® is a unique ad-free, spyware free, and just plain free file sharing application.
EiskaltDC++ - EiskaltDC++ is a program for UNIX-like systems that uses the Direct Connect and ADC protocol.
Shareaza - Shareaza is the most luxurious and sophisticated file sharing system you'll find.
ApexDC++ - ApexDC.net is the home of an innovative P2P program using the Direct Connect and ADC networks.