TwistedBrush Pro Studio - A powerful and unique natural media painting program.
ibis Paint X - Drawn with + ibisPaint
Corel Painter - Corel Painter is media painting software.
Krita - Krita is a professional FREE and open source painting program. It is made by artists that want to seaffordable art tools for everyone. Concept art. texture and matte painters, illustrations and comics.
Huion Sketch - Huion Sketch is an animation and drawing application that comes with all the tools and features, providing you ease when making a painting.
Artrage - A simple but lovely natural media painting and sketching program.